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DICER1 Antikörper (AA 1638-1899)

DICER1 Reaktivität: Maus ICC, IF, WB Wirt: Maus Monoclonal S167-7 unconjugated
Produktnummer ABIN1686625
$474.50
Zzgl. Versandkosten $45.00
100 μg
Lieferung in 3 bis 4 Werktagen
  • Target Alle DICER1 Antikörper anzeigen
    DICER1 (Dicer 1, Ribonuclease Type III (DICER1))
    Bindungsspezifität
    • 15
    • 13
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1638-1899
    Reaktivität
    • 49
    • 24
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 39
    • 25
    • 1
    Maus
    Klonalität
    • 39
    • 26
    Monoklonal
    Konjugat
    • 36
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DICER1 Antikörper ist unkonjugiert
    Applikation
    • 38
    • 16
    • 15
    • 14
    • 13
    • 13
    • 13
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
    Spezifität
    Detects ~215 kDa.
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Protein G Purified
    Immunogen
    Fusion protein amino acids 1638-1899 of mouse Endoribonuclease Dicer
    Klon
    S167-7
    Isotyp
    IgG1
  • Applikationshinweise
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    1 μg/ml of ABIN1686625 was sufficient for detection of Dicer in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C
  • Target
    DICER1 (Dicer 1, Ribonuclease Type III (DICER1))
    Andere Bezeichnung
    Dicer (DICER1 Produkte)
    Synonyme
    dcr1, dicer, herna, DICER1, dicer1, 1110006F08Rik, D12Ertd7e, mKIAA0928, DCR1, Dicer, HERNA, MNG1, DICER, fc39d11, fc74b05, wu:fc39d11, wu:fc74b05, dicer 1, ribonuclease III, endoribonuclease Dicer, dicer 1, ribonuclease III S homeolog, dicer 1, ribonuclease type III, dicer 1 ribonuclease III, DICER1, CpipJ_CPIJ010534, dicer1, dicer1.S, Dicer1
    Hintergrund
    Dicer is a member of the RNase III family that specifically cleaves double-stranded RNAs to generate microRNAs (miRNAs) (1). After long primary transcript pri-miRNAs are processed to stem-looped pre-miRNAs by Drosha (2), pre-miRNAs are transported to the cytoplasm and further processed by Dicer to produce 22-nucleotide mature miRNAs (3). The mature miRNA then becomes a part of the RNA-Induced Silencing Complex (RISC) and can bind to the 3' UTR of the target mRNA (3)
    Gen-ID
    192119
    NCBI Accession
    NP_683750
    UniProt
    Q8R418
    Pathways
    Regulatorische RNA Pathways, Stem Cell Maintenance, Ribonucleoprotein Complex Subunit Organization
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