DICER1 Antikörper (AA 1638-1899)
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- Target Alle DICER1 Antikörper anzeigen
- DICER1 (Dicer 1, Ribonuclease Type III (DICER1))
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Bindungsspezifität
- AA 1638-1899
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Reaktivität
- Maus
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser DICER1 Antikörper ist unkonjugiert
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Applikation
- Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
- Spezifität
- Detects ~215 kDa.
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Protein G Purified
- Immunogen
- Fusion protein amino acids 1638-1899 of mouse Endoribonuclease Dicer
- Klon
- S167-7
- Isotyp
- IgG1
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anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1-195) antibody
DICER1 Reaktivität: Human IHC (p), WB Wirt: Kaninchen Polyclonal unconjugated
anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1638-1899) antibody (HRP)DICER1 Reaktivität: Maus ICC, IF, WB Wirt: Maus Monoclonal S167-7 HRP
anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1638-1899) antibody (FITC)DICER1 Reaktivität: Maus ICC, IF, WB Wirt: Maus Monoclonal S167-7 FITC
anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1638-1899) antibody (Alkaline Phosphatase (AP))DICER1 Reaktivität: Maus ICC, IF, WB Wirt: Maus Monoclonal S167-7 Alkaline Phosphatase (AP)
anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1638-1899) antibody (Biotin)DICER1 Reaktivität: Maus ICC, IF, WB Wirt: Maus Monoclonal S167-7 Biotin
anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1638-1899) antibody (PE)DICER1 Reaktivität: Maus ICC, IF, WB Wirt: Maus Monoclonal S167-7 PE
anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1638-1899) antibody (PerCP)DICER1 Reaktivität: Maus ICC, IF, WB Wirt: Maus Monoclonal S167-7 PerCP
anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1638-1899) antibody (APC)DICER1 Reaktivität: Maus ICC, IF, WB Wirt: Maus Monoclonal S167-7 APC
anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1638-1899) antibody (Atto 488)DICER1 Reaktivität: Maus ICC, IF, WB Wirt: Maus Monoclonal S167-7 Atto 488
anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1638-1899) antibody (Atto 594)DICER1 Reaktivität: Maus ICC, IF, WB Wirt: Maus Monoclonal S167-7 Atto 594
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- Applikationshinweise
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- Kommentare
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1 μg/ml of ABIN1686625 was sufficient for detection of Dicer in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C
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- Target
- DICER1 (Dicer 1, Ribonuclease Type III (DICER1))
- Andere Bezeichnung
- Dicer (DICER1 Produkte)
- Synonyme
- dcr1, dicer, herna, DICER1, dicer1, 1110006F08Rik, D12Ertd7e, mKIAA0928, DCR1, Dicer, HERNA, MNG1, DICER, fc39d11, fc74b05, wu:fc39d11, wu:fc74b05, dicer 1, ribonuclease III, endoribonuclease Dicer, dicer 1, ribonuclease III S homeolog, dicer 1, ribonuclease type III, dicer 1 ribonuclease III, DICER1, CpipJ_CPIJ010534, dicer1, dicer1.S, Dicer1
- Hintergrund
- Dicer is a member of the RNase III family that specifically cleaves double-stranded RNAs to generate microRNAs (miRNAs) (1). After long primary transcript pri-miRNAs are processed to stem-looped pre-miRNAs by Drosha (2), pre-miRNAs are transported to the cytoplasm and further processed by Dicer to produce 22-nucleotide mature miRNAs (3). The mature miRNA then becomes a part of the RNA-Induced Silencing Complex (RISC) and can bind to the 3' UTR of the target mRNA (3)
- Gen-ID
- 192119
- NCBI Accession
- NP_683750
- UniProt
- Q8R418
- Pathways
- Regulatorische RNA Pathways, Stem Cell Maintenance, Ribonucleoprotein Complex Subunit Organization
