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DICER1 Antikörper (AA 1638-1899) (Atto 488)

DICER1 Reaktivität: Maus WB, ICC, IF Wirt: Maus Monoclonal S167-7 Atto 488
Produktnummer ABIN2483003
  • Target Alle DICER1 Antikörper anzeigen
    DICER1 (Dicer 1, Ribonuclease Type III (DICER1))
    Bindungsspezifität
    • 15
    • 11
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1638-1899
    Reaktivität
    • 49
    • 22
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 39
    • 23
    • 1
    Maus
    Klonalität
    • 39
    • 24
    Monoklonal
    Konjugat
    • 36
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DICER1 Antikörper ist konjugiert mit Atto 488
    Applikation
    • 51
    • 17
    • 16
    • 13
    • 13
    • 13
    • 13
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    Detects ~215 kDa.
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Protein G Purified
    Immunogen
    Fusion protein amino acids 1638-1899 of mouse Endoribonuclease Dicer
    Klon
    S167-7
    Isotyp
    IgG1
    Top Product
    Discover our top product DICER1 Primärantikörper
  • Applikationshinweise
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    1 μg/ml of ABIN2483003 was sufficient for detection of Dicer in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Conjugated antibodies should be stored at 4°C
  • Target
    DICER1 (Dicer 1, Ribonuclease Type III (DICER1))
    Andere Bezeichnung
    Dicer (DICER1 Produkte)
    Synonyme
    dcr1 antikoerper, dicer antikoerper, herna antikoerper, DICER1 antikoerper, dicer1 antikoerper, 1110006F08Rik antikoerper, D12Ertd7e antikoerper, mKIAA0928 antikoerper, DCR1 antikoerper, Dicer antikoerper, HERNA antikoerper, MNG1 antikoerper, DICER antikoerper, fc39d11 antikoerper, fc74b05 antikoerper, wu:fc39d11 antikoerper, wu:fc74b05 antikoerper, dicer 1, ribonuclease III antikoerper, endoribonuclease Dicer antikoerper, dicer 1, ribonuclease III S homeolog antikoerper, dicer 1, ribonuclease type III antikoerper, dicer 1 ribonuclease III antikoerper, DICER1 antikoerper, CpipJ_CPIJ010534 antikoerper, dicer1 antikoerper, dicer1.S antikoerper, Dicer1 antikoerper
    Hintergrund
    Dicer is a member of the RNase III family that specifically cleaves double-stranded RNAs to generate microRNAs (miRNAs) (1). After long primary transcript pri-miRNAs are processed to stem-looped pre-miRNAs by Drosha (2), pre-miRNAs are transported to the cytoplasm and further processed by Dicer to produce 22-nucleotide mature miRNAs (3). The mature miRNA then becomes a part of the RNA-Induced Silencing Complex (RISC) and can bind to the 3' UTR of the target mRNA (3)
    Gen-ID
    192119
    NCBI Accession
    NP_683750
    UniProt
    Q8R418
    Pathways
    Regulatorische RNA Pathways, Stem Cell Maintenance, Ribonucleoprotein Complex Subunit Organization
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