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XRCC1 Antikörper (AA 1-320)

XRCC1 Reaktivität: Human IF, IHC, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1683300
$589.88
Zzgl. Versandkosten $45.00
Lieferung in 10 bis 11 Werktagen
  • Target Alle XRCC1 Antikörper anzeigen
    XRCC1 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1))
    Bindungsspezifität
    • 15
    • 10
    • 9
    • 7
    • 7
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-320
    Reaktivität
    • 86
    • 26
    • 24
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 74
    • 12
    Kaninchen
    Klonalität
    • 69
    • 17
    Polyklonal
    Konjugat
    • 38
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser XRCC1 Antikörper ist unkonjugiert
    Applikation
    • 51
    • 35
    • 28
    • 24
    • 18
    • 18
    • 13
    • 13
    • 10
    • 7
    • 3
    • 1
    Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
    Sequenz
    MPEIRLRHVV SCSSQDSTHC AENLLKADTY RKWRAAKAGE KTISVVLQLE KEEQIHSVDI GNDGSAFVEV LVGSSAGGAG EQDYEVLLVT SSFMSPSESR SGSNPNRVRM FGPDKLVRAA AEKRWDRVKI VCSQPYSKDS PFGLSFVRFH SPPDKDEAEA PSQKVTVTKL GQFRVKEEDE SANSLRPGAL FFSRINKTSP VTASDPAGPS YAAATLQASS AASSASPVSR AIGSTSKPQE SPKGKRKLDL NQEEKKTPSK PPAQLSPSVP KRPKLPAPTR TPATAPVPAR AQGAVTGKPR GEGTEPRRPR AGPEELGKIL
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human XRCC1 (NP_006288.2).
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:1000 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    XRCC1 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1))
    Andere Bezeichnung
    XRCC1 (XRCC1 Produkte)
    Synonyme
    xrcc1, MGC80909, XRCC1, rcc, RCC, Xrcc-1, X-ray repair complementing defective repair in Chinese hamster cells 1, X-ray repair cross complementing 1, xrcc1, XRCC1, Xrcc1
    Hintergrund
    The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.,XRCC1,RCC,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cancer,Endocrine & Metabolism,Nucleotide metabolism,Purine and pyrimidine synthesis,XRCC1
    Molekulargewicht
    69 kDa
    Gen-ID
    7515
    UniProt
    P18887
    Pathways
    DNA Reparatur
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