XRCC1 Antikörper (AA 407-435)

Produktnummer ABIN3029645

Produktdetails anti-XRCC1 Antikörper

Target: XRCC1 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1))

Bindungsspezifität: AA 407-435

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XRCC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Flow Cytometry (FACS)

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 407-435 from the human protein was used as the immunogen for this XRCC1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the XRCC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:25,Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the XRCC1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu XRCC1

Target: XRCC1 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1))

Andere Bezeichnung: XRCC1 (XRCC1 Produkte)

Synonyme: xrcc1 antikoerper, MGC80909 antikoerper, XRCC1 antikoerper, rcc antikoerper, RCC antikoerper, Xrcc-1 antikoerper, X-ray repair complementing defective repair in Chinese hamster cells 1 antikoerper, X-ray repair cross complementing 1 antikoerper, xrcc1 antikoerper, XRCC1 antikoerper, Xrcc1 antikoerper

Hintergrund: The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

UniProt: P18887

Pathways: DNA Reparatur