SFRP1 Antikörper (AA 30-314)

Produktnummer ABIN1682676

Der Kaninchen Polyklonal Anti-SFRP1-Antikörper wurde für WB und IHC validiert. Er ist geeignet, SFRP1 in Proben von Human zu detektieren.

Kurzübersicht für SFRP1 Antikörper (AA 30-314) (ABIN1682676)

Target: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SFRP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SFRP1 Antikörper

Bindungsspezifität: AA 30-314

Sequenz: SASEYDYVSF QSDIGPYQSG RFYTKPPQCV DIPADLRLCH NVGYKKMVLP NLLEHETMAE VKQQASSWVP LLNKNCHAGT QVFLCSLFAP VCLDRPIYPC RWLCEAVRDS CEPVMQFFGF YWPEMLKCDK FPEGDVCIAM TPPNATEASK PQGTTVCPPC DNELKSEAII EHLCASEFAL RMKIKEVKKE NGDKKIVPKK KKPLKLGPIK KKDLKKLVLY LKNGADCPCH QLDNLSHHFL IMGRKVKSQY LLTAIHKWDK KNKEFKNFMK KMKNHECPTF QSVFK

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-314 of human SFRP1 (NP_003003.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:100 - 1:500,IHC,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SFRP1

Target: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Andere Bezeichnung: SFRP1

Hintergrund: This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling, epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.,SFRP1,FRP,FRP-1,FRP1,FrzA,SARP2,Cell Biology & Developmental Biology,Apoptosis,Ubiquitin,Wnt/β-Catenin Signaling Pathway,Neuroscience,Stem Cells,SFRP1

Molekulargewicht: 35 kDa

Gen-ID: 6422

UniProt: Q8N474

Pathways: WNT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation