GCLC Antikörper
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- Target Alle GCLC Antikörper anzeigen
- GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser GCLC Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human, Ratte
- Produktmerkmale
- Monoclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- A synthesized peptide derived from human GCLC
- Isotyp
- IgG
- Top Product
- Discover our top product GCLC Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
- Andere Bezeichnung
- GCLC (GCLC Produkte)
- Hintergrund
- Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010],GCL, GCS, GLCL, GLCLC,Apoptosis,Cancer,Cell Biology & Developmental Biology,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial metabolism_Mitochondrial markers,Signal Transduction,GCLC
- Molekulargewicht
- 73 kDa
- Gen-ID
- 2729
- UniProt
- P48506
- Pathways
- Cell RedoxHomeostasis
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