GFRA2 Antikörper (AA 360-464)
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- Target Alle GFRA2 Antikörper anzeigen
- GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))
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Bindungsspezifität
- AA 360-464
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GFRA2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- DVNVSPKGPS FQATQAPRVE KTPSLPDDLS DSTSLGTSVI TTCTSVQEQG LKANNSKELS MCFTELTTNI IPGSNKVIKP NSGPSRARPS AALTVLSVLM LKLAL
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 360-464 of human GFRA2 (NP_001486.4).
- Isotyp
- IgG
- Top Product
- Discover our top product GFRA2 Primärantikörper
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- Applikationshinweise
- WB,1:200 - 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))
- Andere Bezeichnung
- GFRA2 (GFRA2 Produkte)
- Hintergrund
- Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.,GFRA2,GDNFRB,NRTNR-ALPHA,NTNRA,RETL2,TRNR2,Neuroscience,GFRA2
- Molekulargewicht
- 36 kDa/39 kDa/51 kDa
- Gen-ID
- 2675
- UniProt
- O00451
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