GFRA2 Antikörper (AA 360-464)

Produktnummer ABIN1679988

Der Kaninchen Polyklonal Anti-GFRA2-Antikörper wurde für WB validiert. Er ist geeignet, GFRA2 in Proben von Human zu detektieren.

Kurzübersicht für GFRA2 Antikörper (AA 360-464) (ABIN1679988)

Target: GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GFRA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GFRA2 Antikörper

Bindungsspezifität: AA 360-464

Sequenz: DVNVSPKGPS FQATQAPRVE KTPSLPDDLS DSTSLGTSVI TTCTSVQEQG LKANNSKELS MCFTELTTNI IPGSNKVIKP NSGPSRARPS AALTVLSVLM LKLAL

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 360-464 of human GFRA2 (NP_001486.4).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GFRA2

Target: GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

Andere Bezeichnung: GFRA2

Hintergrund: Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.,GFRA2,GDNFRB,NRTNR-ALPHA,NTNRA,RETL2,TRNR2,Neuroscience,GFRA2

Molekulargewicht: 36 kDa/39 kDa/51 kDa

Gen-ID: 2675

UniProt: O00451