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GFRA2 Antikörper (C-Term)

GFRA2 Reaktivität: Human, Maus, Ratte, Pferd, Schwein, Hund, Rind (Kuh), Meerschweinchen, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2785779
  • Target Alle GFRA2 Antikörper anzeigen
    GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    Human, Maus, Ratte, Pferd, Schwein, Hund, Rind (Kuh), Meerschweinchen, Kaninchen
    Wirt
    • 48
    • 2
    • 1
    • 1
    Kaninchen
    Klonalität
    • 50
    • 1
    Polyklonal
    Konjugat
    • 24
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GFRA2 Antikörper ist unkonjugiert
    Applikation
    • 48
    • 24
    • 13
    • 13
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    NVSPKGPSFQ ATQAPRVEKT PSLPDDLSDS TSLGTSVITT CTSVQEQGLK
    Homologie
    Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against GFRA2. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human GFRA2
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    Discover our top product GFRA2 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 464 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))
    Andere Bezeichnung
    GFRA2 (GFRA2 Produkte)
    Synonyme
    GDNFRB antikoerper, NRTNR-ALPHA antikoerper, NTNRA antikoerper, RETL2 antikoerper, TRNR2 antikoerper, Retl2 antikoerper, NTNRALPHA antikoerper, ntnra antikoerper, retl2 antikoerper, trnr2 antikoerper, gdnfrb antikoerper, nrtnr-alpha antikoerper, gfra2 antikoerper, GDNF family receptor alpha 2 antikoerper, glial cell line derived neurotrophic factor family receptor alpha 2 antikoerper, GDNF family receptor alpha 2a antikoerper, GFRA2 antikoerper, Gfra2 antikoerper, gfra2 antikoerper, gfra2a antikoerper
    Hintergrund
    Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. GFRA2 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1.Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: GDNFRB, NRTNR-ALPHA, NTNRA, RETL2, TRNR2
    Protein Interaction Partner: PTEN, NRTN, GDNF,
    Protein Size: 464
    Molekulargewicht
    47 kDa
    Gen-ID
    2675
    NCBI Accession
    NM_001495, NP_001486
    UniProt
    O00451
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