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GFRA2 Antikörper (Middle Region)

GFRA2 Reaktivität: Human, Maus, Ratte WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499885
  • Target Alle GFRA2 Antikörper anzeigen
    GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))
    Bindungsspezifität
    • 15
    • 9
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 51
    • 26
    • 23
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 48
    • 2
    • 1
    • 1
    Kaninchen
    Klonalität
    • 50
    • 1
    Polyklonal
    Konjugat
    • 24
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GFRA2 Antikörper ist unkonjugiert
    Applikation
    • 48
    • 24
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Spezifität
    GFR alpha 2 antibody was raised against a peptide corresponding to amino acids 377 to 391 of human GFR alpha 2.
    Aufreinigung
    DEAE
    Immunogen
    Human GFR alpha 2 Peptide
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA. Western Blot: 1/1000 to 1/2000. A 52 kDa band should be detected. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))
    Andere Bezeichnung
    GFRA2 / GDNFR-beta (GFRA2 Produkte)
    Synonyme
    GDNFRB antikoerper, NRTNR-ALPHA antikoerper, NTNRA antikoerper, RETL2 antikoerper, TRNR2 antikoerper, Retl2 antikoerper, NTNRALPHA antikoerper, ntnra antikoerper, retl2 antikoerper, trnr2 antikoerper, gdnfrb antikoerper, nrtnr-alpha antikoerper, gfra2 antikoerper, GDNF family receptor alpha 2 antikoerper, glial cell line derived neurotrophic factor family receptor alpha 2 antikoerper, GDNF family receptor alpha 2a antikoerper, GFRA2 antikoerper, Gfra2 antikoerper, gfra2 antikoerper, gfra2a antikoerper
    Hintergrund
    Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN), play key roles in the control of vertebrate neuron survival and differentiation. Physiological responses to NTN require the presence of a novel glycosylphosphadidylinositol linked protein NTNRalpha, which is a cell surface receptor for NTN. The cDNAs encoding NTNRa from human, rat, chicken, and mouse have been cloned recently. NTNRalpha was also termed GDNFRbeta, Ret ligand 2 (RETL2) or TGFbeta-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRalpha-2 recently. GFRalpha-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. Thus, NTN, GFRalpha-2, and the Ret PTK form a complex to transduce NTN signal and to mediate NTN function.Synonyms: GDNF family receptor alpha-2, GDNF receptor beta, GDNFRB, GFR-alpha-2, Neurturin receptor alpha, RET ligand 2, RETL2, TGF-beta-related neurotrophic factor receptor 2, TRNR2
    Gen-ID
    2675
    UniProt
    O00451
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