Claudin 11 Antikörper (AA 26-207)

Produktnummer ABIN1679255

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Claudin 11 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Claudin 11 Antikörper (AA 26-207) (ABIN1679255)

Target: Claudin 11 (CLDN11)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Claudin 11 Antikörper

Bindungsspezifität: AA 26-207

Sequenz: STNDWVVTCG YTIPTCRKLD ELGSKGLWAD CVMATGLYHC KPLVDILILP GYVQACRALM IAASVLGLPA ILLLLTVLPC IRMGQEPGVA KYRRAQLAGV LLILLALCAL VATIWFPVCA HRETTIVSFG YSLYAGWIGA VLCLVGGCVI LCCAGDAQAF GENRFYYTAG SSSPTHAKSA HV

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 26-207 of human CLDN11 (NP_005593.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Claudin 11

Target: Claudin 11 (CLDN11)

Andere Bezeichnung: CLDN11

Hintergrund: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.,CLDN11,OSP,OTM,Immunology & Inflammation,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Oligodendrocyte marker,CLDN11

Molekulargewicht: 21 kDa

Gen-ID: 5010

UniProt: O75508

Pathways: Hepatitis C