LIF Antikörper

Produktnummer ABIN1589935

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch LIF in WB. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für LIF Antikörper (ABIN1589935)

Target: LIF (Leukemia Inhibitory Factor (LIF))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LIF Antikörper

Verwendungszweck: LIF antibody

Spezifität: Recombinant mouse LIF

Produktmerkmale: Chromosomal location: 11 A1-A2, 11 00.25 cM
Produced from sera of rabbits immunized with highly pure recombinant mouse Leukemia Inhibitory Factor (LIF) [Ser24 - Phe203, produced in E. coli].

Aufreinigung: Anti-human LIF was purified by affinity chromatography with immobilized Protein A.

Immunogen: Recombinant mouse LIF (ABIN1589657)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: use at 2-5 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS

Handhabung: Centrifuge vial prior to opening.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

Haltbarkeit: 24 months

Details zu LIF

Target: LIF (Leukemia Inhibitory Factor (LIF))

Andere Bezeichnung: LIF

Hintergrund: Lif,Leukemia Inhibitory Factor also called LIF is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78 % identity in its amino acid sequence. Human LIF is as active on human cells as is it is on mouse cells, though mouse LIF is about 1000 fold less active on human cells, than human LIF.

Gen-ID: 16878

NCBI Accession: NM_008501, NP_032527

UniProt: P09056

Pathways: JAK-STAT Signalweg, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Stem Cell Maintenance, Growth Factor Binding