PODXL Antikörper

Produktnummer ABIN1589722

Dieses Maus Monoklonal-Antikörper erkennt spezifisch PODXL in IF und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PODXL Antikörper (ABIN1589722)

Target: PODXL (Podocalyxin-Like (PODXL))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PODXL Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: GB6D9

Produktdetails anti-PODXL Antikörper

Spezifität: Membrane protein fraction of isolated human glomeruli

Produktmerkmale: Chromosomal location: 7q32-q33
Monoclonal antibodies were produced with the help of BALB/c mice using a membrane protein fraction of isolated human glomeruli as the immunizing antigen.

Aufreinigung: The mouse IgG1 antibody (#4D5aE5E6) from hybridomas was purified from cell culture supernatant by Protein G chromatography.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: IF/IHC: use at 2-5 µg/mL.

Kommentare:

Monoclonal Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS

Handhabung: Centrifuge vial prior to opening.

Lagerung: -20 °C

Informationen zur Lagerung: The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.

Haltbarkeit: 6 months

Details zu PODXL

Target: PODXL (Podocalyxin-Like (PODXL))

Andere Bezeichnung: Podocalyxin

Hintergrund: Podocalyxin is the major sialoprotein in the glycocalyx of glomerular podocytes. It was shown that endothelial cell membranes contain Podocalyxin. By immunoelectron microscopy Podocalyxin was localized on the luminal membrane domain of endothelial cells, in a patchy distribution. The presence of Podocalyxin was confirmed in SDS extracts of lung tissue by immunoblotting. It is concluded that (a) Podocalyxin is a widespread component of endothelial plasma membranes, (b) it is restricted to the luminal membrane domain, and (c) it is distributed unevenly on the endothelial cell surface.
Synonyms: PODXL, PC, PCLP, Gp200, PCLP-1, Podocalyxin-like protein, GCTM-2 antigen, Gp200

NCBI Accession: NM_001018111, NP_001018121

UniProt: O00592

Pathways: Tube Formation