Der Maus Monoklonal Anti-NEFL-Antikörper wurde für WB, IHC, IF und ICC validiert. Er ist geeignet, NEFL in Proben von Human, Ratte, Maus, Schwein, Rind (Kuh) und Säugetier zu detektieren.
NEFL
Reaktivität: Schwein
WB, IF
Wirt: Maus
Monoclonal
DA2
unconjugated
Applikationshinweise
For immunofluorescence, use MCA-7D1 diluted 1/100 to 1/500. For western blots try MCA-7D1 diluted 1/5,000 to 1:10,000.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 4°C short term or -20°C long term.
Target
NEFL
(Neurofilament, Light Polypeptide (NEFL))
Andere Bezeichnung
Neurofilament NF-L
Hintergrund
Neurofilaments are the 10 nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-L is the neurofilament light or low molecular weight polypeptide and runs on SDS-PAGE gels at about 68 kDa. Antibodies to NF-L are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-L antibody can also be useful in the diagnostics of neurofilament accumulations seen in many neurological diseases, such as Lou Gehrig's disease and Alzheimer's disease. Mutations in the protein coding region of the human NF-L gene cause some forms of Charcot-Marie-Tooth disease.