NEFL Antikörper

Produktnummer ABIN1580446

Dieses Maus Monoklonal-Antikörper erkennt spezifisch NEFL in WB, IHC, IF und ICC. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Schwein, Rind (Kuh) und Säugetier.

Kurzübersicht für NEFL Antikörper (ABIN1580446)

Target: NEFL (Neurofilament, Light Polypeptide (NEFL))

Reaktivität: Human, Ratte, Maus, Schwein, Rind (Kuh), Säugetier

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NEFL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: DA2

Produktdetails anti-NEFL Antikörper

Aufreinigung: conc. tissue culture supernatant

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: For immunofluorescence, use MCA-DA2 diluted 1/500. For western blots try MCA-DA2 diluted 1/10,000 to 1:20,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4°C short term or -20°C long term.

Details zu NEFL

Target: NEFL (Neurofilament, Light Polypeptide (NEFL))

Andere Bezeichnung: Neurofilament NF-L

Hintergrund: Neurofilaments are the 10 nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-L is the neurofilament light or low molecular weight polypeptide and runs on SDS-PAGE gels at about 68 kDa. Antibodies to NF-L are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-L antibody can also be useful in the diagnostics of neurofilament accumulations seen in many neurological diseases, such as Lou Gehrig's disease and Alzheimer's disease. Mutations in the protein coding region of the human NF-L gene cause some forms of Charcot-Marie-Tooth disease. This antibody has been sold by Chemicon and Millipore for many years under the catalog number Mab1615, and has been used in numerous publications. The same antibody is also marketed, more expensively, by Abcam, Novus and many other companies.