TANK Antikörper

Produktnummer ABIN155084

Produktdetails anti-TANK Antikörper

Target: TANK (TRAF Family Member-Associated NFKB Activator (TANK))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TANK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Spezifität: This antibody detects TANK.

Aufreinigung: Affinity purified

Immunogen: Synthetic peptide surrounding amino acid 413 of human TANK

Anwendungsinformationen

Applikationshinweise: Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 10-20 μg/mL. Immunohistochemistry: 10-20 μg/mL. Mouse small intestine tissue lysate can be used as a positive control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: PBS pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Details zu TANK

Target: TANK (TRAF Family Member-Associated NFKB Activator (TANK))

Andere Bezeichnung: TANK / ITRAF (TANK Produkte)

Synonyme: I-TRAF antikoerper, ITRAF antikoerper, TRAF2 antikoerper, C86182 antikoerper, E430026L09Rik antikoerper, zgc:153048 antikoerper, i-traf antikoerper, tank antikoerper, traf2 antikoerper, TRAF family member associated NFKB activator antikoerper, TRAF family member-associated Nf-kappa B activator antikoerper, TRAF family member-associated NFKB activator antikoerper, TRAF family member associated NFKB activator L homeolog antikoerper, TANK antikoerper, Tank antikoerper, tank antikoerper, tank.L antikoerper

Hintergrund: Members of TRAF family associate with activated TNF-R and CD40 and have been implicated to induce nuclear translocation of NFκB. TANK can bind to all three TRAFs and synergizing with TRAF2 to activate the NFκB signal cascade.Synonyms: I-TRAF, TRAF family member-associated NF-kappa-B activator, TRAF-interacting protein, TRAF2

Gen-ID: 10010

NCBI Accession: NP_001186064

UniProt: Q92844

Pathways: p53 Signalweg, TLR Signalweg, Activation of Innate immune Response