Der Kaninchen-Polyklonal Anti-TANK-Antikörper wurde für WB, IHC (p) und IP validiert. Er ist geeignet zum Nachweis von TANK in Proben aus Human, Maus und Ratte.
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Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 10-20 μg/mL. Immunohistochemistry: 10-20 μg/mL. Mouse small intestine tissue lysate can be used as a positive control. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
-20 °C/-80 °C
Informationen zur Lagerung
Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
Target
TANK
(TRAF Family Member-Associated NFKB Activator (TANK))
Andere Bezeichnung
TANK / ITRAF
Hintergrund
Members of TRAF family associate with activated TNF-R and CD40 and have been implicated to induce nuclear translocation of NFκB. TANK can bind to all three TRAFs and synergizing with TRAF2 to activate the NFκB signal cascade.Synonyms: I-TRAF, TRAF family member-associated NF-kappa-B activator, TRAF-interacting protein, TRAF2