PODXL Antikörper (C-Term)

Produktnummer ABIN1540003

Dieses Maus Monoklonal-Antikörper erkennt spezifisch PODXL in WB und IF. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für PODXL Antikörper (C-Term) (ABIN1540003)

Target: PODXL (Podocalyxin-Like (PODXL))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PODXL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Klon: 632CT5-11-4

Produktdetails anti-PODXL Antikörper

Bindungsspezifität: AA 410-439, C-Term

Aufreinigung: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This PODXL antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 410-439 amino acids from the C-terminal region of human PODXL.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: IF: 1:100. WB: 1:16000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: PODXL Antibody (C-term)(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Referenzen für anti-PODXL Antikörper (ABIN1540003)

San, Prost, Williams, Moss, Nuber: "High Podocalyxin levels promote cell viability partially through up-regulation of Annexin A2." in: Biochemical and biophysical research communications, Vol. 478, Issue 2, pp. 573-9, (2016) (PubMed).

Details zu PODXL

Target: PODXL (Podocalyxin-Like (PODXL))

Andere Bezeichnung: PODXL

Hintergrund: This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.

Molekulargewicht: 58635

Gen-ID: 5420

NCBI Accession: NP_001018121, NP_005388

UniProt: O00592

Pathways: Tube Formation