Tuberin Antikörper

Produktnummer ABIN1539797

Der Maus Monoklonal Anti-Tuberin Antikörper wurde für WB und IF validiert. Er ist geeignet, Tuberin in Proben von Maus zu detektieren.

Kurzübersicht für Tuberin Antikörper (ABIN1539797)

Target: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Tuberin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Klon: 249CT19-1-3

Produktdetails anti-Tuberin Antikörper

Aufreinigung: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This TSC2 monoclonal antibody is generated from mouse immunized with TSC2 recombinant protein.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: TSC2 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu Tuberin

Target: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Andere Bezeichnung: TSC2

Hintergrund: Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht: 200608

Gen-ID: 7249

NCBI Accession: NP_000539, NP_001070651, NP_001107854

UniProt: P49815

Pathways: RTK Signalweg, AMPK Signaling, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus