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PARP1 Antikörper (pSer782)

Dieses Anti-PARP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PARP1 in DB. Geeignet für Human.
Produktnummer ABIN1539777

Kurzübersicht für PARP1 Antikörper (pSer782) (ABIN1539777)

Target

Alle PARP1 Antikörper anzeigen
PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Reaktivität

  • 243
  • 66
  • 51
  • 10
  • 7
  • 5
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 227
  • 39
  • 1
Kaninchen

Klonalität

  • 211
  • 56
Polyklonal

Konjugat

  • 164
  • 16
  • 15
  • 13
  • 12
  • 12
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser PARP1 Antikörper ist unkonjugiert

Applikation

  • 176
  • 125
  • 68
  • 56
  • 45
  • 42
  • 40
  • 39
  • 24
  • 17
  • 16
  • 7
  • 7
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Dot Blot (DB)

Klon

RB39169
  • Bindungsspezifität

    • 16
    • 15
    • 15
    • 12
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer782

    Homologie

    B, Ha, M, Rat

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This PARP1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S782 of human PARP1.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    DB: 1:500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Phospho-PARP1-S782 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

    Haltbarkeit

    6 months
  • Target

    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

    Andere Bezeichnung

    PARP1

    Hintergrund

    This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

    Molekulargewicht

    113084

    Gen-ID

    142

    NCBI Accession

    NP_001609

    UniProt

    P09874

    Pathways

    Apoptose, Caspase Kaskade in der Apoptose, DNA Reparatur, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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