Integrin beta 2 Antikörper (N-Term)

Produktnummer ABIN1539259

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Integrin beta 2 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Integrin beta 2 Antikörper (N-Term) (ABIN1539259)

Target: Integrin beta 2 (ITGB2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Integrin beta 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB38888

Produktdetails anti-Integrin beta 2 Antikörper

Bindungsspezifität: AA 272-300, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ITGB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-300 amino acids from the N-terminal region of human ITGB2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: ITGB2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu Integrin beta 2

Target: Integrin beta 2 (ITGB2)

Andere Bezeichnung: ITGB2

Hintergrund: The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.

Molekulargewicht: 84782

Gen-ID: 3689

NCBI Accession: NP_000202, NP_001120963

UniProt: P05107

Pathways: NF-kappaB Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation