desert Hedgehog Antikörper (AA 195-223)

Produktnummer ABIN1538035

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch desert Hedgehog in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für desert Hedgehog Antikörper (AA 195-223) (ABIN1538035)

Target: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser desert Hedgehog Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB39505

Produktdetails anti-desert Hedgehog Antikörper

Bindungsspezifität: AA 195-223

Homologie: M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DHH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the Central region of human DHH.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: DHH Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu desert Hedgehog

Target: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Andere Bezeichnung: DHH

Substanzklasse: Species

Hintergrund: This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved, the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.

Molekulargewicht: 43577

Gen-ID: 50846

NCBI Accession: NP_066382

UniProt: O43323

Pathways: Hedgehog Signalweg