Acetyl-CoA Carboxylase alpha Antikörper (C-Term)

Produktnummer ABIN1536835

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Acetyl-CoA Carboxylase alpha in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Acetyl-CoA Carboxylase alpha Antikörper (C-Term) (ABIN1536835)

Target: Acetyl-CoA Carboxylase alpha (ACACA)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Acetyl-CoA Carboxylase alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB37458

Produktdetails anti-Acetyl-CoA Carboxylase alpha Antikörper

Bindungsspezifität: AA 2010-2039, C-Term

Homologie: B, M, Rat, Sh

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ACACA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2010-2039 amino acids from the C-terminal region of human ACACA.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: ACACA Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu Acetyl-CoA Carboxylase alpha

Target: Acetyl-CoA Carboxylase alpha (ACACA)

Andere Bezeichnung: ACACA

Hintergrund: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.

Molekulargewicht: 265554

Gen-ID: 31

NCBI Accession: NP_942131, NP_942133, NP_942134, NP_942135, NP_942136

UniProt: Q13085

Pathways: AMPK Signaling, Ribonucleoside Biosynthetic Process, Warburg Effekt