Prokineticin Receptor 1 Antikörper (AA 19-68)

Produktnummer ABIN1535984

Der Kaninchen Polyklonal anti-Prokineticin Receptor 1 Antikörper (ABIN1535984) detektiert spezifisch Prokineticin Receptor 1 in ELISA, WB, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Prokineticin Receptor 1 Antikörper (AA 19-68) (ABIN1535984)

Target: Prokineticin Receptor 1 (PROKR1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Prokineticin Receptor 1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Prokineticin Receptor 1 Antikörper

Bindungsspezifität: AA 19-68

Verwendungszweck: PKR1 Antibody

Spezifität: PKR1 Polyclonal Antibody detects endogenous levels of PKR1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PKR1. AA range:19-68

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000, IF ICC 1:100-500,ELISA 1:5000-20000,IHC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Prokineticin Receptor 1

Target: Prokineticin Receptor 1 (PROKR1)

Andere Bezeichnung: PKR1

Hintergrund:

Synonyms: PROKR1, GPR73, PKR1, Prokineticin receptor 1, PK-R1, G-protein coupled receptor 73, G-protein coupled receptor ZAQ, GPR73a

Background: prokineticin receptor 1(PROKR1) Homo sapiens This gene encodes a member of the G-protein-coupled receptor family. The encoded protein binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. The encoded protein is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. The protein may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in this gene may be associated with recurrent miscarriage. [provided by RefSeq, Aug 2016],

Gene Name: PROKR1

Protein Name: Prokineticin receptor 1

Molekulargewicht: 44 kDa

Gen-ID: 10887

OMIM: 607122

UniProt: Q8TCW9

Pathways: Hedgehog Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma