Prokineticin Receptor 1 Antikörper (AA 30-110)

Produktnummer ABIN7216600

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Prokineticin Receptor 1 in ELISA, WB, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Prokineticin Receptor 1 Antikörper (AA 30-110) (ABIN7216600)

Target: Prokineticin Receptor 1 (PROKR1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Prokineticin Receptor 1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Prokineticin Receptor 1 Antikörper

Bindungsspezifität: AA 30-110

Verwendungszweck: Rabbit Anti-PKR1 Polyclonal Antibody

Spezifität: PKR1 Polyclonal Antibody detects endogenous levels of PKR1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human PKR1 at AA range: 30-110

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IF/ICC1:100-500,ELISA 1:5000-20000,IHC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Prokineticin Receptor 1

Target: Prokineticin Receptor 1 (PROKR1)

Andere Bezeichnung: PKR1

Hintergrund: PROKR1, GPR73, PKR1, Prokineticin receptor 1, PK-R1, G-protein coupled receptor 73, G-protein coupled receptor ZAQ, GPR73aPROKR1 encodes a member of the G-protein-coupled receptor family. prokineticin receptor 1 binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. Prokineticin receptor 1 is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. Prokineticin receptor 1 may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in PROKR1 may be associated with recurrent miscarriage.

Molekulargewicht: 45kD

Gen-ID: 10887

UniProt: Q8TCW9

Pathways: Hedgehog Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma