Adenosine A3 Receptor Antikörper (AA 255-304)

Produktnummer ABIN1535643

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Adenosine A3 Receptor in WB, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Adenosine A3 Receptor Antikörper (AA 255-304) (ABIN1535643)

Target: Adenosine A3 Receptor (ADORA3)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adenosine A3 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-Adenosine A3 Receptor Antikörper

Bindungsspezifität: AA 255-304

Verwendungszweck: Adenosine A3-R Antibody

Spezifität: Adenosine A3-R Polyclonal Antibody detects endogenous levels of Adenosine A3-R protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ADORA3. AA range:255-304

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Adenosine A3 Receptor

Target: Adenosine A3 Receptor (ADORA3)

Andere Bezeichnung: ADORA3

Hintergrund:

Synonyms: ADORA3; Adenosine receptor A3

Background: This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Alternative splicing results in multiple transcript variants. This gene shares its 5' terminal exon with some transcripts from overlapping GeneID:57413, which encodes an immunoglobulin domain-containing protein. [provided by RefSeq, Nov 2014],

Gene Name: ADORA3

Protein Name: Adenosine receptor A3

Molekulargewicht: 36 kDa

Gen-ID: 140

OMIM: 600445

UniProt: P33765

Pathways: Hormone Transport, cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process