Fibulin 5 Antikörper (AA 171-220)

Produktnummer ABIN1534905

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Fibulin 5 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Fibulin 5 Antikörper (AA 171-220) (ABIN1534905)

Target: Fibulin 5 (FBLN5)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fibulin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Fibulin 5 Antikörper

Bindungsspezifität: AA 171-220

Verwendungszweck: Fibulin-5 Antibody

Spezifität: Fibulin-5 Polyclonal Antibody detects endogenous levels of Fibulin-5 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human FBLN5. AA range:171-220

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Fibulin 5

Target: Fibulin 5 (FBLN5)

Andere Bezeichnung: FBLN5

Hintergrund:

Synonyms: FBLN5, DANCE, Fibulin-5, FIBL-5, Developmental arteries and neural crest EGF-like protein, Dance, Urine p50 protein, UP50

Background: The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore,The protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq, Jul 2008],

Gene Name: FBLN5

Protein Name: Fibulin-5

Molekulargewicht: 50 kDa

Gen-ID: 10516

OMIM: 604580

UniProt: Q9UBX5

Pathways: SARS-CoV-2 Protein Interaktom