POLE Antikörper (AA 1261-1310)
Kurzübersicht für POLE Antikörper (AA 1261-1310) (ABIN1534837)
Target
Alle POLE Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1261-1310
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Verwendungszweck
- DNA pol ε A Antibody
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Spezifität
- DNA pol ε A Polyclonal Antibody detects endogenous levels of DNA pol ε A protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human POLE1. AA range:1261-1310
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Isotyp
- IgG
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Applikationshinweise
- IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- POLE (Polymerase (DNA Directed), Epsilon, Catalytic Subunit (POLE))
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Andere Bezeichnung
- POLE1
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Hintergrund
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Synonyms: POLE, POLE1, DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit A
Background: DNA polymerase epsilon, catalytic subunit(POLE) Homo sapiens This gene encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in this gene have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature. [provided by RefSeq, Sep 2013],
Gene Name: POLE
Protein Name: DNA polymerase epsilon catalytic subunit A
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Molekulargewicht
- 261 kDa
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Gen-ID
- 5426
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OMIM
- 174762
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UniProt
- Q07864
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Pathways
- Telomere Maintenance, DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
Target
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