DOCK1 Antikörper (AA 1661-1710)

Produktnummer ABIN1534823

Der Kaninchen Polyklonal anti-DOCK1 Antikörper (ABIN1534823) detektiert spezifisch DOCK1 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für DOCK1 Antikörper (AA 1661-1710) (ABIN1534823)

Target: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DOCK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-DOCK1 Antikörper

Bindungsspezifität: AA 1661-1710

Verwendungszweck: DOCK 180 Antibody

Spezifität: DOCK 180 Polyclonal Antibody detects endogenous levels of DOCK 180 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human DOCK1. AA range:1661-1710

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu DOCK1

Target: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Andere Bezeichnung: DOCK1

Hintergrund:

Synonyms: DOCK1, Dedicator of cytokinesis protein 1, 180 kDa protein downstream of CRK, DOCK180

Background: This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014],

Gene Name: DOCK1

Protein Name: Dedicator of cytokinesis protein 1

Molekulargewicht: 215 kDa

Gen-ID: 1793

OMIM: 601403

UniProt: Q14185

Pathways: Signaling of Hepatocyte Growth Factor Receptor