MUTYH Antikörper (AA 151-200)
Kurzübersicht für MUTYH Antikörper (AA 151-200) (ABIN1534474)
Target
Alle MUTYH Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 151-200
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Verwendungszweck
- MYH Antibody
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Spezifität
- MYH Polyclonal Antibody detects endogenous levels of MYH protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human MUTYH. AA range:151-200
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- MUTYH (MutY Homolog (E. Coli) (MUTYH))
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Andere Bezeichnung
- MUTYH
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Hintergrund
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Synonyms: MUTYH, MYH, A/G-specific adenine DNA glycosylase, MutY homolog, hMYH
Background: This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Gene Name: MUTYH
Protein Name: A/G-specific adenine DNA glycosylase
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Molekulargewicht
- 60 kDa
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Gen-ID
- 4595
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OMIM
- 137215
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UniProt
- Q9UIF7
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Pathways
- DNA Reparatur
Target
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