MSH3 Antikörper (AA 51-100)

Produktnummer ABIN1534472

Der Kaninchen Polyklonal anti-MSH3 Antikörper (ABIN1534472) detektiert spezifisch MSH3 in WB, IHC, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für MSH3 Antikörper (AA 51-100) (ABIN1534472)

Target: MSH3 (MutS Homolog 3 (MSH3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MSH3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-MSH3 Antikörper

Bindungsspezifität: AA 51-100

Verwendungszweck: MSH3 Antibody

Spezifität: MSH3 Polyclonal Antibody detects endogenous levels of MSH3 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MSH3. AA range:51-100

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu MSH3

Target: MSH3 (MutS Homolog 3 (MSH3))

Andere Bezeichnung: MSH3

Hintergrund:

Synonyms: MSH3, DUC1, DUG, DNA mismatch repair protein Msh3, hMSH3, Divergent upstream protein, DUP, Mismatch repair protein 1, MRP1

Background: The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq, Mar 2011],

Gene Name: MSH3

Protein Name: DNA mismatch repair protein Msh3

Molekulargewicht: 127 kDa

Gen-ID: 4437

OMIM: 600887

UniProt: P20585

Pathways: DNA Reparatur, Production of Molecular Mediator of Immune Response