MSH2 Antikörper (AA 541-590)
Kurzübersicht für MSH2 Antikörper (AA 541-590) (ABIN1534471)
Target
Alle MSH2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 541-590
-
Verwendungszweck
- MSH2 Antibody
-
Spezifität
- MSH2 Polyclonal Antibody detects endogenous levels of MSH2 protein.
-
Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Reinheit
- > 95 %
-
Immunogen
- The antiserum was produced against synthesized peptide derived from human MSH2. AA range:541-590
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C/1 year
-
Haltbarkeit
- 12 months
-
-
- MSH2 (Mismatch Repair Protein 2 (MSH2))
-
Andere Bezeichnung
- MSH2
-
Hintergrund
-
Synonyms: MSH2, DNA mismatch repair protein Msh2, hMSH2, MutS protein homolog 2
Background: This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012],
Gene Name: MSH2
Protein Name: DNA mismatch repair protein Msh2
-
Molekulargewicht
- 104 kDa
-
Gen-ID
- 4436
-
OMIM
- 120435
-
UniProt
- P43246
-
Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
Target
-