MLH1 Antikörper (AA 441-490)
Kurzübersicht für MLH1 Antikörper (AA 441-490) (ABIN1534468)
Target
Alle MLH1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 441-490
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Verwendungszweck
- MLH1 Antibody
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Spezifität
- MLH1 Polyclonal Antibody detects endogenous levels of MLH1 protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human MLH1. AA range:441-490
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-2000,IHC 1:50-300
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- MLH1 (MutL Homolog 1 (MLH1))
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Andere Bezeichnung
- MLH1
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Hintergrund
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Synonyms: MLH1, COCA2, DNA mismatch repair protein Mlh1, MutL protein homolog 1
Background: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009],
Gene Name: MLH1
Protein Name: DNA mismatch repair protein Mlh1
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Molekulargewicht
- 84 kDa
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Gen-ID
- 4292
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OMIM
- 120436
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UniProt
- P40692
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Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
Target
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