FGF23 Antikörper (AA 151-200)

Produktnummer ABIN1534408

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-FGF23 Antikörper wird verwendet zum Nachweis von FGF23 in Proben von Human, Ratte und Maus. Er wurde validiert für WB, ELISA und IF.

Kurzübersicht für FGF23 Antikörper (AA 151-200) (ABIN1534408)

Target: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGF23 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-FGF23 Antikörper

Bindungsspezifität: AA 151-200

Verwendungszweck: FGF-23 Antibody

Spezifität: FGF-23 Polyclonal Antibody detects endogenous levels of FGF-23 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human FGF23. AA range:151-200

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Referenzen für anti-FGF23 Antikörper (ABIN1534408)

Sun, Zou, Yang, Morita, Gong, Shiba, Akagawa, Yuan: "Inorganic polyphosphates stimulate FGF23 expression through the FGFR pathway." in: Biochemical and biophysical research communications, Vol. 428, Issue 2, pp. 298-302, (2012) (PubMed).

Details zu FGF23

Target: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Andere Bezeichnung: FGF23

Hintergrund:

Synonyms: FGF23, HYPF, Fibroblast growth factor 23, FGF-23, Phosphatonin, Tumor-derived hypophosphatemia-inducing factor

Background: This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013],

Gene Name: FGF23

Protein Name: Fibroblast growth factor 23

Molekulargewicht: 27 kDa

Gen-ID: 8074

OMIM: 193100

UniProt: Q9GZV9

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Negative Regulation of Hormone Secretion