Cadherin-16 Antikörper (AA 780-829)

Produktnummer ABIN1534285

Der Kaninchen Polyklonal anti-Cadherin-16 Antikörper wird verwendet zum Nachweis von Cadherin-16 in Proben von Human, Maus und Ratte. Er wurde validiert für IHC, WB, IF und ELISA.

Kurzübersicht für Cadherin-16 Antikörper (AA 780-829) (ABIN1534285)

Target: Cadherin-16 (CDH16)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cadherin-16 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), ELISA

Produktdetails anti-Cadherin-16 Antikörper

Bindungsspezifität: AA 780-829

Verwendungszweck: Cadherin-16 Antibody

Spezifität: Cadherin-16 Polyclonal Antibody detects endogenous levels of Cadherin-16 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CDH16. AA range:780-829

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Cadherin-16

Target: Cadherin-16 (CDH16)

Andere Bezeichnung: CDH16

Hintergrund:

Synonyms: CDH16, Cadherin-16, Kidney-specific cadherin, Ksp-cadherin

Background: This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011],

Gene Name: CDH16

Protein Name: Cadherin-16

Molekulargewicht: 89 kDa

Gen-ID: 1014

OMIM: 603118

UniProt: O75309