TLE2 Antikörper (AA 211-260)

Produktnummer ABIN1533832

Der Kaninchen Polyklonal anti-TLE2 Antikörper wird verwendet zum Nachweis von TLE2 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für TLE2 Antikörper (AA 211-260) (ABIN1533832)

Target: TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLE2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-TLE2 Antikörper

Bindungsspezifität: AA 211-260

Verwendungszweck: TLE2 Antibody

Spezifität: TLE2 Polyclonal Antibody detects endogenous levels of TLE2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human TLE2. AA range:211-260

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu TLE2

Target: TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))

Andere Bezeichnung: TLE2

Hintergrund:

Synonyms: TLE2, Transducin-like enhancer protein 2, Enhancer of split groucho-like protein 2, ESG2

Background: function:Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.,similarity:Belongs to the WD repeat Groucho/TLE family.,similarity:Contains 6 WD repeats.,subunit:Homooligomer and heterooligomer with other family members. Binds LEF1, TCF7, TCF7L1, TCF7L2, UTY, HES1 and HES5.,tissue specificity:In all tissues examined, mostly in heart, brain, and muscle.,

Gene Name: TLE2

Protein Name: Transducin-like enhancer protein 2

Molekulargewicht: 79 kDa

Gen-ID: 7089

OMIM: 601041

UniProt: Q04725

Pathways: WNT Signalweg