MYBL1 Antikörper (AA 231-280)

Produktnummer ABIN1533606

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MYBL1 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für MYBL1 Antikörper (AA 231-280) (ABIN1533606)

Target: MYBL1 (Myb-Like Protein 1 (MYBL1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYBL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MYBL1 Antikörper

Bindungsspezifität: AA 231-280

Verwendungszweck: A-Myb Antibody

Spezifität: A-Myb Polyclonal Antibody detects endogenous levels of A-Myb protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MYB-A. AA range:231-280

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu MYBL1

Target: MYBL1 (Myb-Like Protein 1 (MYBL1))

Hintergrund:

Synonyms: MYBL1, AMYB, Myb-related protein A, A-Myb, Myb-like protein 1

Background: function:Strong transcriptional activator, DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Could have a role in the proliferation and/or differentiation of neurogenic, spermatogenic and B-lymphoid cells.,similarity:Contains 3 HTH myb-type DNA-binding domains.,subunit:Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL2.,tissue specificity:Expressed in a variety of lymphoid and solid tumor lines cultured in vitro.,

Gene Name: MYBL1

Protein Name: Myb-related protein A

Molekulargewicht: 85 kDa

Gen-ID: 4603

OMIM: 159405

UniProt: P10243

Pathways: Zellzyklus, Chromatin Binding