Presenilin 1 Antikörper (pSer357)
Kurzübersicht für Presenilin 1 Antikörper (pSer357) (ABIN1532166)
Target
Alle Presenilin 1 (PSEN1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 323-372, pSer357
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Spezifität
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PSEN1 (Phospho-Ser357) Antibody detects endogenous levels of PSEN1 only when phosphorylated at Ser357.
PhosphorylationH:S357 M:S357 R:S358
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Aufreinigung
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human PSEN1 around the phosphorylation site of Ser357.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:5000
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Kommentare
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Unigene-Number: Hs.3260 (NCBI Gene Symbol: PSEN1)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable at -20°C for at least 1 year.
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Haltbarkeit
- 12 months
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- Presenilin 1 (PSEN1)
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Andere Bezeichnung
- PSEN1
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Hintergrund
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Synonyms: AD3, AD3H, presenilin 1, PS-1, PS1, PSN1, PSNL1, S182 protein
NCBI Gene Symbol: PSEN1
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Molekulargewicht
- 52 kDa
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Gen-ID
- 5663
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OMIM
- 104311
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UniProt
- P49768
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Pathways
- Notch Signalweg, EGFR Signaling Pathway, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
Target
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