EGFR Antikörper (pTyr1197)
Kurzübersicht für EGFR Antikörper (pTyr1197) (ABIN1531822)
Target
Alle EGFR Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1161-1210, pTyr1197
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Spezifität
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EGFR (Phospho-Tyr1197) Antibody detects endogenous levels of EGFR only when phosphorylated at Tyr1197.
PhosphorylationH:Y1197 M:Y1197 R:Y1196
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Aufreinigung
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human EGFR around the phosphorylation site of Tyr1197.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000
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Kommentare
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Unigene-Number: Hs.488293 (NCBI Gene Symbol: EGFR)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable at -20°C for at least 1 year.
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Haltbarkeit
- 12 months
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- EGFR (Epidermal Growth Factor Receptor (EGFR))
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Andere Bezeichnung
- EGFR
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Hintergrund
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Synonyms: Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1 , EGFR , ERBB1
NCBI Gene Symbol: EGFR
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Molekulargewicht
- 134 kDa
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Gen-ID
- 1956
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OMIM
- 131550
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UniProt
- P00533
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Pathways
- NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine
Target
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