CHEK2 Antikörper (pThr383)
Kurzübersicht für CHEK2 Antikörper (pThr383) (ABIN1531498)
Target
Alle CHEK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 356-405, pThr383
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Spezifität
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Chk2 (Phospho-Thr383) Antibody detects endogenous levels of Chk2 only when phosphorylated at Thr383.
PhosphorylationH:T383 M:T387 R:T386
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Aufreinigung
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human Chk2 around the phosphorylation site of Thr383.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:20000
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Kommentare
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Unigene-Number: Hs.291363, Hs.505297 (NCBI Gene Symbol: CHEK2)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable at -20°C for at least 1 year.
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Haltbarkeit
- 12 months
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- CHEK2 (Checkpoint Kinase 2 (CHEK2))
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Andere Bezeichnung
- Chk2
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Hintergrund
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Synonyms: Cds1, CHEK2, CHK2, Chk2, CHK2 checkpoint homolog (S. pombe), kinase Chk2, RAD53
NCBI Gene Symbol: CHEK2
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Molekulargewicht
- 60 kDa
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Gen-ID
- 11200
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OMIM
- 176807
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UniProt
- O96017
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Pathways
- p53 Signalweg, Apoptose, Zellzyklus
Target
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