ADAM17 Antikörper (pThr735)
Kurzübersicht für ADAM17 Antikörper (pThr735) (ABIN1531481)
Target
Alle ADAM17 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 701-750, pThr735
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Spezifität
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ADAM 17 (Phospho-Thr735) Antibody detects endogenous levels of ADAM 17 only when phosphorylated at Thr735.
PhosphorylationH:T735 M:T735 R:T735
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Aufreinigung
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human ADAM 17 around the phosphorylation site of Thr735.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500~1:1000 ELISA: 1:20000
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Kommentare
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Unigene-Number: Hs.404914 (NCBI Gene Symbol: ADAM17)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable at -20°C for at least 1 year.
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Haltbarkeit
- 12 months
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Parallel age-associated changes in brain and plasma neuronal pentraxin receptor levels in a transgenic APP/PS1 rat model of Alzheimer's disease." in: Neurobiology of disease, Vol. 74, pp. 32-40, (2015) (PubMed).
: "
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Parallel age-associated changes in brain and plasma neuronal pentraxin receptor levels in a transgenic APP/PS1 rat model of Alzheimer's disease." in: Neurobiology of disease, Vol. 74, pp. 32-40, (2015) (PubMed).
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- ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
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Andere Bezeichnung
- ADAM 17
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Hintergrund
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Synonyms: ADA17, ADAM 17, CD156b antigen, CSVP, TACE, TNF-alpha convertase, TNF-alpha-converting enzyme, a disintegrin and metalloproteinase domain 17, snake venom-like protease
NCBI Gene Symbol: ADAM17
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Molekulargewicht
- 93 kDa
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Gen-ID
- 6868
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OMIM
- 603639
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UniProt
- P78536
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Pathways
- Notch Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Response to Growth Hormone Stimulus
Target
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