Insulin Receptor Antikörper (pTyr972)
Kurzübersicht für Insulin Receptor Antikörper (pTyr972) (ABIN1495716)
Target
Alle Insulin Receptor (INSR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pTyr972
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Spezifität
- Human and mouse IR. Rat (100 % homologous) IR has not been tested, but is expected to react. IGF1R [pY950] (75 % homologous) has been shown to cross-react in some cell systems
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Aufreinigung
- Immunoaffinity purified
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Immunogen
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Synthetic phosphopeptide derived from the region of the human insulin receptor that contains tyrosine 972, as numbered according to Ebina, et al. (tyrosine 960 according to Ulrich, et al.). The sequence is conserved in mouse and rat.
Type of Immunogen: Synthetic phospho-peptide
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Applikationshinweise
- Approved: WB (1:1000)
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Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Dulbecco's PBS (without Mg2+, Ca2+), pH 7.3 (+/- 0.1), 50 % glycerol, 1.0 mg/mL BSA (IgG, protease free) as a carrier.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Insulin Receptor (INSR)
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Andere Bezeichnung
- Insulin Receptor
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Hintergrund
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Name/Gene ID: INSR
Subfamily: Insulin receptor
Family: Protein Kinase
Synonyms: INSR, CD220, ILP receptor, Insulin receptor, IR, HHF5, CD220 antigen -
Gen-ID
- 3643
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UniProt
- P06213
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Pathways
- NF-kappaB Signalweg, RTK Signalweg, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
Target
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