SIRT1 Antikörper (AA 577-590)
Kurzübersicht für SIRT1 Antikörper (AA 577-590) (ABIN1493902)
Target
Alle SIRT1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 577-590
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Spezifität
- Human SIRT1. This antibody is expected to recognize both reported isoforms (NP_036370.2, NP_001135970.1).
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Homologie
- Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%) Mouse (93%) Rat (86%).
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Aufreinigung
- Immunoaffinity purified
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Immunogen
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Synthetic peptide C-EKPQEVQTSRNVES from an internal region of human SIRT1 (NP_036370.2, NP_001135970.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%), Mouse (93%), Rat (86%).
Type of Immunogen: Synthetic peptide
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anti-Sirtuin 1 (SIRT1) (AA 101-200) antibody
SIRT1 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Sirtuin 1 (SIRT1) (AA 448-747) antibodySIRT1 Reaktivität: Human WB, IHC, IP, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Sirtuin 1 (SIRT1) (AA 456-555) antibodySIRT1 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 7B7 unconjugated
anti-Sirtuin 1 (SIRT1) (AA 566-601), (C-Term) antibodySIRT1 Reaktivität: Human, Maus WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB50965 unconjugated
anti-Sirtuin 1 (SIRT1) antibodySIRT1 Reaktivität: Human WB, IHC, ELISA, ICC, FACS Wirt: Maus Monoclonal 1F3 unconjugated
anti-Sirtuin 1 (SIRT1) antibodyKO Validated SIRT1 Reaktivität: Human WB, IHC, IP, IF, ChIP Wirt: Kaninchen Polyclonal unconjugated
anti-Sirtuin 1 (SIRT1) (N-Term) antibodySIRT1 Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
anti-Sirtuin 1 (SIRT1) (AA 566-601) antibodySIRT1 Reaktivität: Human, Maus WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Sirtuin 1 (SIRT1) (AA 456-555) antibodySIRT1 Reaktivität: Human WB, IF, IHC (p), EIA Wirt: Maus Monoclonal 7B7 unconjugated
anti-Sirtuin 1 (SIRT1) (AA 244-498) antibodySIRT1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:64000), WB (0.05 - 0.2 μg/mL)
Usage: Peptide ELISA: antibody detection limit dilution 1:64000. Western blot: Approx 120kD band observed in lysates of cell line Jurkat (calculated MW of 81.7kD according to NP_036370.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Cheng et al, Proc Natl Acad Sci U S A. 2003 Sep 16,100(19):10794-9., PMID: 12960381). Recommended concentration: 0.05-0.2 μg/mL. -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Tris-buffered saline, pH 7.3, 0.5 % BSA, 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Minimize freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze-thaw cycles.
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- SIRT1 (Sirtuin 1 (SIRT1))
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Andere Bezeichnung
- SIRT1 / Sirtuin 1
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Hintergrund
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Name/Gene ID: SIRT1
Family: ADP-Ribosyltransferase
Synonyms: SIRT1, SIR2-like protein 1, SIR2alpha, SIR2L1, Sirtuin 1, Sir2-like 1, Sirtuin type 1, HSIR2, HSIRT1 -
Gen-ID
- 23411
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NCBI Accession
- NP_036370, NP_001135970
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UniProt
- Q96EB6
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Pathways
- MAPK Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling
Target
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