OCRL Antikörper (AA 150-199)

Produktnummer ABIN1453701

Der Kaninchen Polyklonal anti-OCRL Antikörper (ABIN1453701) detektiert spezifisch OCRL in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für OCRL Antikörper (AA 150-199) (ABIN1453701)

Target: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OCRL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-OCRL Antikörper

Bindungsspezifität: AA 150-199

Verwendungszweck: OCRL Antibody

Spezifität: OCRL Polyclonal Antibody detects endogenous levels of OCRL protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human OCRL. AA range:150-199

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu OCRL

Target: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Andere Bezeichnung: OCRL

Hintergrund:

Synonyms: OCRL, INPP5F, OCRL1, Inositol polyphosphate 5-phosphatase OCRL-1, Lowe oculocerebrorenal syndrome protein

Background: This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],

Gene Name: OCRL

Protein Name: Inositol polyphosphate 5-phosphatase OCRL-1

Molekulargewicht: 104 kDa

Gen-ID: 4952

OMIM: 300535

UniProt: Q01968

Pathways: Inositol Metabolic Process