Interleukin enhancer-binding factor 3 (ILF3) (AA 302-351) Antikörper

Produktnummer ABIN1453638

Der Kaninchen Polyklonal anti-Interleukin enhancer-binding factor 3 Antikörper (ABIN1453638) detektiert spezifisch Interleukin enhancer-binding factor 3 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Interleukin enhancer-binding factor 3 (ILF3) (AA 302-351) Antikörper (ABIN1453638)

Target: Interleukin enhancer-binding factor 3 (ILF3)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails

Bindungsspezifität: AA 302-351

Verwendungszweck: NF90 Antibody

Spezifität: NF90 Polyclonal Antibody detects endogenous levels of NF90 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human NF90. AA range:302-351

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Antigendetails

Target: Interleukin enhancer-binding factor 3 (ILF3)

Andere Bezeichnung: NF90

Hintergrund:

Synonyms: ILF3, DRBF, MPHOSPH4, NF90, Interleukin enhancer-binding factor 3, Double-stranded RNA-binding protein 76, DRBP76, M-phase phosphoprotein 4, MPP4, Nuclear factor associated with dsRNA, NFAR, Nuclear factor of activated T-cells 90 kDa, NF-AT-90, Translational control protein 80, TCP80

Background: This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2014],

Gene Name: ILF3

Protein Name: Interleukin enhancer-binding factor 3

Molekulargewicht: 95 kDa

Gen-ID: 3609

OMIM: 603182

UniProt: Q12906

Pathways: M Phase