TANK Antikörper (AA 171-220)

Produktnummer ABIN1450959

Der Kaninchen Polyklonal anti-TANK Antikörper (ABIN1450959) detektiert spezifisch TANK in WB, IHC, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für TANK Antikörper (AA 171-220) (ABIN1450959)

Target: TANK (TRAF Family Member-Associated NFKB Activator (TANK))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TANK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-TANK Antikörper

Bindungsspezifität: AA 171-220

Verwendungszweck: TANK Antibody

Spezifität: TANK Polyclonal Antibody detects endogenous levels of TANK protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human TANK. AA range:171-220

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu TANK

Target: TANK (TRAF Family Member-Associated NFKB Activator (TANK))

Andere Bezeichnung: I-TRAF

Hintergrund:

Synonyms: TANK, ITRAF, TRAF2, TRAF family member-associated NF-kappa-B activator, TRAF-interacting protein, I-TRAF

Background: The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily.The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example,The protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010],

Gene Name: TANK

Protein Name: TRAF family member-associated NF-kappa-B activator

Molekulargewicht: 47 kDa

Gen-ID: 10010

OMIM: 603893

UniProt: Q92844

Pathways: p53 Signalweg, TLR Signalweg, Activation of Innate immune Response