TBK1 Antikörper (AA 138-187)
Kurzübersicht für TBK1 Antikörper (AA 138-187) (ABIN1450668)
Target
Alle TBK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 138-187
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Verwendungszweck
- TBK1 Antibody
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Spezifität
- TBK1 Polyclonal Antibody detects endogenous levels of TBK1 protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- The antiserum was produced against synthesized peptide derived from human TBK1. AA range:138-187
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Isotyp
- IgG
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Applikationshinweise
- IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- TBK1 (TANK-Binding Kinase 1 (TBK1))
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Andere Bezeichnung
- TBK1
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Hintergrund
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Synonyms: TBK1, NAK, Serine/threonine-protein kinase TBK1, NF-kappa-B-activating kinase, T2K, TANK-binding kinase 1
Background: The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex.The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010],
Gene Name: TBK1
Protein Name: Serine/threonine-protein kinase TBK1
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Molekulargewicht
- 83 kDa
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Gen-ID
- 29110
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OMIM
- 604834
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UniProt
- Q9UHD2
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Pathways
- TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interaktom
Target
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