TET3 Antikörper (C-Term)

Produktnummer ABIN1449990

Der Kaninchen Polyklonal anti-TET3 Antikörper (ABIN1449990) detektiert spezifisch TET3 in WB, IF und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für TET3 Antikörper (C-Term) (ABIN1449990)

Target: TET3 (Tet Methylcytosine Dioxygenase 3 (TET3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TET3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-TET3 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: A 17 amino acid synthetic peptide near the carboxy terminus of Human TET3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu TET3

Target: TET3 (Tet Methylcytosine Dioxygenase 3 (TET3))

Andere Bezeichnung: MGC22014

Hintergrund: TET3, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine and is most abundantly expressed in hematopoietic cells. Unlike the related TET2 protein, mutations in TET3 have not been observed in any myeloid malignancies. TET3 has been shown to be involved in the demethylation of zygotic DNA before the first mitosis and has been suggested to be involved in the epigenetic reprogramming of the zygotic paternal DNA following natural fertilization and may also contribute to somatic cell nuclear reprogramming during animal cloning.Synonyms: KIAA0401, TET3

Molekulargewicht: 183 kDa

Gen-ID: 200424

NCBI Accession: NP_659430

Pathways: Warburg Effekt