ATG14 Antikörper (Middle Region)

Produktnummer ABIN1449976

Produktdetails anti-ATG14 Antikörper

Target: ATG14 (ATG14 Autophagy Related 14 (ATG14))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: ATG14 antibody was raised against an 18 amino acid synthetic peptide near the center of Human ATG14

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ATG14

Target: ATG14 (ATG14 Autophagy Related 14 (ATG14))

Andere Bezeichnung: ATG14 / Barkor (ATG14 Produkte)

Synonyme: ATG14L antikoerper, BARKOR antikoerper, KIAA0831 antikoerper, 4832427M01 antikoerper, Atg14L antikoerper, D14Ertd114e antikoerper, D14Ertd436e antikoerper, RGD1304610 antikoerper, autophagy related 14 antikoerper, ATG14 antikoerper, Atg14 antikoerper

Hintergrund: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein ATG1. ATG14 is a subunit of a class III phosphatidylinositol (PtdIns) 3-kinase complex that targets the complex to the endoplasmic reticulum, the site of autophagosome formation.Synonyms: Atg14L, Beclin 1-associated autophagy-related key regulator, KIAA0831

Molekulargewicht: 54 kDa

Gen-ID: 22863

NCBI Accession: NP_055739

Pathways: Autophagie