PVRL2 Antikörper
Kurzübersicht für PVRL2 Antikörper (ABIN1449206)
Target
Alle PVRL2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Spezifität
- This antibody reacts with human CD112 antigen.
-
Aufreinigung
- Protein G agarose
-
Immunogen
- Recombinant human CD112
-
Isotyp
- IgG2a
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1.0 mg/mL
-
Buffer
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
-
Konservierungsmittel
- Without preservative
-
Handhabung
- Avoid repeated freezing and thawing.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Upon receipt, store (in aliqouts) at -20 °C.
-
-
- PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
-
Andere Bezeichnung
- CD112 / Nectin 2
-
Hintergrund
- CD112, also known as Poliovirus Receptor Related 2 (PRR2), is a transmembrane glycoprotein that functions as the receptor for alpha-herpes virus and pseudorabies virus entry into the cell. CD112 has been shown to be identical to Nectin-2, an adhesion protein localized to adherens junctions. CD112 is widely expressed in neuronal, endothelial, and in particular, epithelial cells, where it is found at the intercellular junctions of adjacent cells. Additionally CD112 is detected on hematopoietic progenitors expressing CD34, where it plays a role in the regulation of hematopoietic/endothelial cell interactions. At least two isoforms of CD112 mRNA have been identified.Synonyms: HVEB, Herpes virus entry mediator B, Nectin-2, PRR2, PVRL2, Poliovirus receptor-related protein 2
-
Gen-ID
- 5819
-
NCBI Accession
- NP_001036189
-
UniProt
- Q92692
-
Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization
Target
-