PVRL2 Antikörper

Produktnummer ABIN1449206

Der Ratte Monoklonal Anti-PVRL2-Antikörper wurde für FACS validiert. Er ist geeignet, PVRL2 in Proben von Human zu detektieren.

Kurzübersicht für PVRL2 Antikörper (ABIN1449206)

Target: PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser PVRL2 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: TX31

Produktdetails anti-PVRL2 Antikörper

Spezifität: This antibody reacts with human CD112 antigen.

Aufreinigung: Protein G agarose

Immunogen: Recombinant human CD112

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Upon receipt, store (in aliqouts) at -20 °C.

Details zu PVRL2

Target: PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))

Andere Bezeichnung: CD112 / Nectin 2

Hintergrund: CD112, also known as Poliovirus Receptor Related 2 (PRR2), is a transmembrane glycoprotein that functions as the receptor for alpha-herpes virus and pseudorabies virus entry into the cell. CD112 has been shown to be identical to Nectin-2, an adhesion protein localized to adherens junctions. CD112 is widely expressed in neuronal, endothelial, and in particular, epithelial cells, where it is found at the intercellular junctions of adjacent cells. Additionally CD112 is detected on hematopoietic progenitors expressing CD34, where it plays a role in the regulation of hematopoietic/endothelial cell interactions. At least two isoforms of CD112 mRNA have been identified.Synonyms: HVEB, Herpes virus entry mediator B, Nectin-2, PRR2, PVRL2, Poliovirus receptor-related protein 2

Gen-ID: 5819

NCBI Accession: NP_001036189

UniProt: Q92692

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization